The obligate intracellular bacterium Orientia tsutsugamushi differentiates into a developmentally distinct extracellular state

The obligate intracellular bacterium Orientia tsutsugamushi differentiates into a developmentally distinct extracellular state

Blog Article

Orientia tsutsugamushi (Ot) the causing agent of scrub typhus exits infected cells using a unique mechanism that involves budding off the Fan Shop - Oilers - Clothing surface of infected cells.Here, Atwal et al.report that Ots that have budded from their host cells are in a distinct developmental stage than intracellular bacteria and provide the first characterization of this extracellular stage.Both forms are infectious but differ in their physical properties, proteome, and 110 entry mechanism into host cells.